Effective and validated animal models are valuable to investigate the pathogenesis and potential therapeutics for\nhuman diseases. There is much concern for diabetic retinopathy (DR) in that it affects substantial number of\nworking population all around the world, resulting in visual deterioration and social deprivation. In this review, we\ndiscuss animal models of DR based on different species of animals from zebrafish to monkeys and prerequisites for\nanimal models. Despite criticisms on imprudent use of laboratory animals, we hope that animal models of DR will\nbe appropriately utilized to deepen our understanding on the pathogenesis of DR and to support our struggle to\nfind novel therapeutics against catastrophic visual loss from DR.
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